Download Video
So easy and cheap :p dont know why you use DCM to extract the ephedrine freebase the toulene or xylene polarity is better for extracting freebases and dont form side product when adding NaOH, do you know what stereoisomers of ephedrine are produced is it reacemic ?
 
By employing this method all four diastereoisomers will be formed in variable concentration, one chiral carbon atom (the one with the nitrogen) will have its chirality dictated by the ephedrone. The oxo(keto) reduction yields racemic alcohols with borohydride but carrot slices can do the trick and finish with a single pair of enantiomers, the tedious workup would become the problem in this case.
 
By employing this method all four diastereoisomers will be formed in variable concentration, one chiral carbon atom (the one with the nitrogen) will have its chirality dictated by the ephedrone. The oxo(keto) reduction yields racemic alcohols with borohydride but carrot slices can do the trick and finish with a single pair of enantiomers, the tedious workup would become the problem in this case.
I think that the best way would be make ephedrine reduction to get racemic meth and make the enantiomer resolution.
 
I think that the best way would be make ephedrine reduction to get racemic meth and make the enantiomer resolution.
In that case not many advantages than P2P route.
Another option could be make the enantiomer resolution to the ephedrone but not sure how it will works and you would keep the levo isomer to later process the levo ephedrine to reduce it and obtain dextro meth.
 
I think that the best way would be make ephedrine reduction to get racemic meth and make the enantiomer resolution.
Resolving ephedrine before reducing it to meth would be so stupid that nobody with the actual skill to resolve it would ever do it in practice. Therefore you are right.
 
I think the only shortcoming of this video is that it doesn't split the ephedrine because what you get is mixed ephedrine. I think no one in our forum is willing to split ephedrine and share the video. If someone does, he is a great chemist. Or a better way is to reduce it to mixed methamphetamine and then split it
 
I think the only shortcoming of this video is that it doesn't split the ephedrine because what you get is mixed ephedrine. I think no one in our forum is willing to split ephedrine and share the video. If someone does, he is a great chemist. Or a better way is to reduce it to mixed methamphetamine and then split it
Here is a video doing what you're talking about separation of the isomers L & Dextro...
 
ph better have 6-5.5 because u get more pure product and then dont need wash with acetone. when is more pure then get nice glass crystal. Not need use ph2 or ph4 is tu much acid then product is much more dirty.
the same u can throw first acid and get ph 6 and then use 3x water.
Whe know when is pure if color water is the same no change color on yellow or orange then we know with what pure liquid we work.
 
So easy and cheap :p dont know why you use DCM to extract the ephedrine freebase the toulene or xylene polarity is better for extracting freebases and dont form side product when adding NaOH, do you know what stereoisomers of ephedrine are produced is it reacemic ?
Separation of racemate into enantiomers is a headache and many hours of work. But the fact remains that reducing a mixture of ephedrine isomers with HI in the presence of red P as a catalyst will result in a racemic mixture of methamphetamine isomers that will surpass D-methamphetamine alone in terms of taste and effects. This is just my own opinion about my experience in this matter, because, after all, discussing flavors is a waste of calories.
 
In that case not many advantages than P2P route.
Another option could be make the enantiomer resolution to the ephedrone but not sure how it will works and you would keep the levo isomer to later process the levo ephedrine to reduce it and obtain dextro meth.
Yeah btcboss2022 I was reading on some of the original workups, way back when they first started employing synthetic routes to (-)ephedrine, > resolved intermediate prior to reduction to E, then another rxn ( I don’t recall the catalys, they did use one though) to yield (+)PSE
I like The idea of getting the racemate isolated early then carying out rx to desired product. To bad methylamine is asymmetric.. you on to any chiral rxn from ketone? I know Hydrogenlysis shit looks a bit over My head
 
Yeah btcboss2022 I was reading on some of the original workups, way back when they first started employing synthetic routes to (-)ephedrine, > resolved intermediate prior to reduction to E, then another rxn ( I don’t recall the catalys, they did use one though) to yield (+)PSE
I like The idea of getting the racemate isolated early then carying out rx to desired product. To bad methylamine is asymmetric.. you on to any chiral rxn from ketone? I know Hydrogenlysis shit looks a bit over My head
you on to any chiral rxn from ketone?
I only know reductive amination with (S)-alpha-Methylbenzylamine.
 
When you download this video you get the Ephedrine Crystallization video not this video of Ephedrine HCl Synthesis
 

Media information

Category
Synthesis of Methcathinones
Added by
Novator
Date added
View count
8,430
Comment count
25
Rating
4.50 star(s) 2 ratings
  • Free product samples

    Testing products from new vendors and manufacturers.

    Get free samples for testing now!

  • Always stay in touch with BB forum. Element/Matrix.

    Connect notifications to always stay in touch with the forum!

    Connect

  • The BB Forum team is looking for cooperation:

    • Traffic arbitrage specialists
    • Spammers
    • Advertising agencies
    • Bloggers/Vloggers
    • TOR sites directories
    • Creative people who can create viral content
    • Administrators of Telegram Channels and Groups

      We will pay more for your traffic than our competitors! $0.1 per visitor!!!If you are interested in, write to the administrator.
Top