BENZPHETAMIN-HYDROCHLORIDE, an overlooked Meth advancement....

RE-Surfaced...RE-Cooked...RE-Creational_JOY

Look what Your Homie with the Gasmask Unveiled to my sweet "Bad-BreakazZ"
Don`t Knew that? well this is my favourite BuzZ....
ONE STEP CLOSER TOWARDS ENLIGHTENMENT

Be NICE stay HIGH
Dr. rer.nat. ELEUZUZ


N-Benzyl-N-methylamphetamine
Benzphetamine Hydrochloride (former Didrex)

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Benzphetamine is a sympathomimetic amine
mono amine releasing / STIMULANT type
(slightly higher serotonine releasing nm-spec., then its metabolites)

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Benzphetamine is metabolized by the human body
into amphetamine and methamphetamine,
[ prodrug of dextromethamphetamine and dextroamphetamine ]
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Amphetamine and related sympathomimetic medications (such as benzphetamine) are thought to stimulate the release of norepinephrine and/or dopamine from storage sites in nerve terminals of the lateral hypothalamic feeding center, thereby producing a decrease in appetite. This release is mediated through the binding of benzphetamine to VMAT2 and inhibiting its function, causing a release of these neurotransmitters into the synaptic cleft through their reuptake transporters. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class.
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Common Dosages: 25 mg - 100 mg

Benzphetamine has a half-life of 4 to 6 hours.
(16 to 31 Hrs. incl. Metabolites)

Mandellin-Reagent, Color identifier.: bright Yellow./Green

melting point: 129-130 °C

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Prepa

ration of Benzphetamine Hydrochloride

[ Scaled for 10g Methamphetamine-HCL ]
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Materials Needed:​

• Methamphetamine Hydrochloride: 10 g
• Potassium Carbonate: 11.60 g
• Benzyl Chloride: 4.61 g
• Water: 50 mL (reaction medium)
• Sodium Hydroxide Solution: (for pH adjustment to ~13)
• Naphtha: 50 mL per extraction (3 extractions total)
• Distilled Water
  additional (for titration): 80 mL
• 15% Hydrochloric Acid Solution: (sufficient quantity to adjust pH to 4-5)
• Isopropanol:100 mL
• Acetone: (sufficient for washing and crystallization)

Equipment Needed:​

• Reaction vessel
• Magnetic stirrer with stir bar
• pH meter or pH indicator strips
• Separatory funnel
• Evaporating dish (Pyrex preferred)
• Filtration setup

---

Step-by-Step Procedure:​

1. Dissolution of Starting Material:​

• Dissolve 10 g of methamphetamine hydrochloride in 50mL of water in a clean reaction vessel at room temperature.

2. Addition of Potassium Carbonate:​

• Slowly add 11.60 g of potassium carbonate to the solution while stirring.
• Continue stirring for 30 minutes to ensure complete reaction.

3. Benzylation Reaction:​

• Add 4.61 g of benzyl chloride to the mixture.
• Heat the reaction mixture to 70-75°C and maintain this temperature for 10 hours with continuous stirring.
• let it cool to room temperature with additional stirring.
• Dilute with 100 ml cool water. stir and let it rest 5 minutes

4. Basification:​

• After completion of the reaction, cooing and diluting the mixture,
• Adjust the pH to approximately 13 using sodium hydroxide solution, monitoring with a pH meter./strips

5. Extraction:​

• Perform three consecutive extractions using 50 mL of naphtha for each extraction.
• Combine the naphtha layers in a separate vessel containing 80 mL of distilled water.
  -> pour the Naphtha extracts on top of aqueous layer, (will stay on top...)

6. Acidification to Form Hydrochloride Salt:​

• Equip the vessel with a magnetic stir bar and gradually titrate with 15% hydrochloric acid.
• Add the acid in small portions, stirring vigorously after each addition.
• Monitor the pH after each addition until it reaches 4-5.
• After reaching the desired pH, continue stirring vigorously for an additional 30 minutes to
  ensure complete conversion of the freebase ( from Naphtha Layer) to the hydrochloride salt (then dissolved in the DH2O Layer!).

7. Isolation of the Hydrochloride Salt:​

• Separate the aqueous layer containing the hydrochloride salt. (discard the Naphtha layer, store, to reuse , its perfectly fine again)
• Add 100 mL of isopropanol to the aqueous layer and concentrate the mixture by evaporation (to speed up evaping process!)
  under ventilation with constant slight magnetic stirring in a Pyrex evaporating dish until most of the liquid has evaporated.

8. Crystallization:​

• Remove the stir bar and perform flash crystallization by adding a sufficient amount of acetone.
• Collect the crude crystalline mass, dry it, and rinse three times with generous portions of acetone.

9. Recrystallization:​

• Dissolve the washed salt conglomerate in a heated saturated isopropanol solution.
• Remove the solution from the heat source and allow it to stand undisturbed to promote slow crystallization.

10. Final Drying:​

• Once crystallization is complete, rinse with cold acetone if necessary, and dry thoroughly

 

[Eleusius_hive_reboot]

The CONVERSION IN MY EXPERIMENT; WAS QUANTITATIVE ~98% yield

subjectively it is superior to meth.... feels like 4-MMC & D-Meth combined.

 

[ruen]

Is it smokeable though?

 

[Eleusius_hive_reboot]

Hahahaha.....ITS THE BEST AND WISEST QUESTION and i edit in
the propertie description.....


YES YOU CAN VERY WELL BLAST A BOWL PIPE WITH THAT FEED !

 

[ruen]

great! will try soon

 

[loadingST]

Im intrested have you tried the product of amphetamine and benzyl chloride vs benzmeth ?

 

[Eleusius_hive_reboot]

no i haven't done this, i got no really literature references to consider it , as well as synthesizing it, because, working with benzyl-chloride is a hassle- its a lachrymator (strong tear gas like properties) and even the cleanup of glassware is tedious...

so for Benz-Fat (i like to refer to it as) i had the curiousity, that it could be beneficial / exciting new experience...and it always is....just if i am bored enough every few years of the good old d-ice...then its gonna be time to BENZ-FAT my stash ....YO!