Amphetamine synthesis from P2NP via Al/Hg (video)

[danil1398]

Hello, I have some question:

1. Can Red Bull aluminum be used?
2. Can aluminum be used from aluminum meat trays?
3. When we tried to make Mercury Nitrate, we had a reaction that the mercury melted and became an increasingly clear yellow liquid with an intense smell - where did we make a mistake? We added about 1g of Mercury to the pot and then added about 3.5 ml of 65% nitric acid. A yellow foam appeared in the reaction, there was no rise in temperature. We currently have such a product and have no idea how to get crystals. Should we heat it, boil it and then cool it?

Thank you for your answers

 

[ASheSChem]

3. you don't need crystal; put 10ml acid nitric with your 1gr of mercury; and use 5ml of the yellow liquid for your aluminum

 

[ACAB]

You must heat the solution to 60 degrees otherwise no mercury (II) nitrate will be formed, and provide an air vent the brown gas that is produced is very toxic.

Since many cans in the food industry are made of tinplate you must be sure that it is aluminum, then it might work.

 

[Gale]

Reporting back on the salting MDMA base with sulphuric acid.

MDMA sulphate = poo

Based it and hit it with HCl. Don't try to go sulphate with MDMA its a waste of time. Maybe phosphate but just stick with HCl. Lol

 

[cyb3r0]

Is acetone or isobol a substitute for dichloromethane?

 

[ACAB]

For what purpose?
When it is a case of shaking amphetamine out of an aqueous phase, acetone and IPA are rather poorly qualified. You can use petroleum ether instead.

 

[cyb3r0]

For washing amphetamine

 

[yin-yang]

two questions

1. Can i mix 65% NNO3 and Hg from thermometer to get mercury (II) nitrate. How much acid do I need to mix?

2. Preparing a solution of sulphuric acid in acetone- is this water sensitive? my h2so4 is about 50% PH 1 and my acetone isn't anhydrous, can i use that without sacrificing the yield? or do i need to dry out acetone and concentrate my H2SO4 to its azeotrope of 98%

 

[ASheSChem]

1. There are several manufacturing standards for clinical thermometers: In the Russian thermometer, usually between 1 and 1.5 g of mercury occurs. In Europe - 2 g. Now there are models of Russian thermometers made according to European standards, so that they can also contain 2 g.
---> For one thermometer 20ml of nitric acid gives 3 to 4x 5ml of liquid mercury nitrate. What is useful for 3 to 4x12gr of aluminum

2. you need 96%+

 

[ACAB]

I would use dry and icecold acetone for washing the amphetamine and not dichloromethane, which is for extracting of an aqueous phase.

 

[TerminusEst]

I would like to know something about recovering solvents in this particular reaction, really just to lower cost and reduce my footprint.
As far as i understand it the final layer consists of (in terms of solvents) IPA and then sulfuric acid in acetone is added wich means that after the solution is made neutral and the amphetamine is collected i should be left with a mixture of acetone, IPA and whatever sodium hydroxide and sulfuric acid neutralize themself into.
Acetone has a Boiling point of 56 C and IPA of 82 C so is it possible and advisable to recover the solvents by distillation ?
I don't have a fractionating column so I guess it would mean that the recovered acetone is contaminated with IPA and the IPA would contain some acetone, what would be the implications for reuse of them ? what purity do i need to achieve for them to be reusable as solvents ?

 

[ACAB]

I also recover as much solvent as possible, but always separate acetone and isopropanol. I also do not use acetone with sulfuric acid, but also isopropanol. It is not possible to completely prevent mixing. I perform a distillation and use a column filled with small glass tubes to get the surface as large as possible. I find it important to dry the solvents, because water in the solvents reduces the yield. There are several possibilities, in the meantime I have even assembled a solvent recovery apparatus myself, because I use it again and again, mostly after a few syntheses.

There is also a topic where I have commented on this several times.

http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/threads/solvents-recovery.937/

 

[TerminusEst]

So i could substitute the acetone with more IPA distill it after use and use the procedure described under 1) in the solvents recovery Thread ?
That would be great becuase it would make recovering the solvents so much easier since you only have to think about the IPA.

 

[ACAB]

Yes, you can. But acetone is also used to wash the sulfate later, but you can recover it just the same way. Distill and dry. Also remember that isopropanol forms an azeotropic mixture with water.

 

[danil1398]

Thanks for the answers so far, they helped. We succeeded from the third attempt, yield 70%. The look, structure, color and work are perfect, only the smell of acetone bothers me terribly I have a few more questions:

1. What if I put more mercury nitrate instead of 5ml say 7ml, what will happen?
2. Can I finally use 50ml ISO (isopropyl alcohol) + 2ml sulfuric acid instead of 50ml acetone + 2ml sulfuric acid? I ask this because acetone is aggressive and leaves a pungent odor and in some recipes, ie syntheses I have seen that they use ISO instead of Acetone

 

[WillD]

The reaction can begin faster and more exothermic.
Then you will have to evaporate alcohol, as it does not crystallize amphetamine even in the freezer. Acetone is needed, and after complete drying, acetone has no smell. Perhaps your acetone is not pure.

 

[ACAB]

Sry, first time i heard about that, i used IPA for all my Syntheses and it works. You can also use methanol or ethanol to precipitate the sulfate.
Why would this not work, I ask for explanation!?
It may be possible that acetone is the best solvent for precipitation, but that it does not work with IPA, etc., is not true.

 

[WillD]

When there is a large amount of alcohol, the powder is poorly crystallized. Amphetamine is almost not dissolved in cold acetone (unlike alcohol), and even the usual adding acetone to alcohol crystallizes powder in seconds. No need to misinform people.

 

[WillD]

But for the amalgam reaction, alcohol is certainly the best choice. But not for crystallization, if its volume is large on the amount of the base of amphetamine.

 

[ACAB]

The safety data sheet from amphetamine sulfate says poorly soluble in ethanol 96%, then this should also apply to isopropanol and methanol, shouldn't it?
The info confuses me right now, because in practice plenty of sulfate precipitates also in IPA.