Izomerizacija kanabidiola (CBD) v psihoaktivne kanabinoide

[kitboy]

Kuhal sem CBD in mešanici pomotoma dodal NAoh, mislim, da se je izomerizacija ustavila. Nastali sta 2 plasti, ali mi lahko kdo pove, kaj je nastalo? Ali je to dober način za pridobivanje ekstrakta THC?

Uporabljam metanol in HCL

 

[G.Patton]

Pozdravljeni, v kateri fazi ste dodali NaOH?

Odgovor lahko dobite z analizo HPLC.

 

[kitboy]

Po dveh urah izomerizacije je nastalo olje, ki pa ima neprijeten vonj in ne vem, kako ga očistiti.

 

[kitboy]

Ob dodajanju Naoh sta se fazi ločili in mislim, da se je reakcija ustavila. Poskušal sem jo oprati na več načinov, vendar se ne morem znebiti tega neprijetnega vonja.

 

[cvvvxa]

baze pretvorijo cbd (thc se ne pretvori) v nekatere derivate kinona. mislim, da se lahko za ločevanje od thc uporabijo različna topila, vendar se ne spomnim, v kateri literaturi je bilo to opisano tudi zato, ker je zelen (domnevam), da se lahko oksidirajo tudi nekateri rastlinski nečistoče

 

[kitboy]

Kaj je boljša ocetna ali klorovodikova kislina? Ostalo mi je olje z odvratnim vonjem, ki ga naredim, da ga očistim ali izločim čiste cbd loas iz metanola

 

[cvvvxa]

s toluenom in p-toluensulfonsko kislino pri sobni temperaturi lahko pridobimo skoraj čisto delta 9, z drugimi topili s segrevanjem pa dobimo delta 8

 

[cvvvxa]

toluen je morda težko odstraniti, vendar, 44h (48h bo povzročilo nekoliko večjo pretvorbo, vendar približno 10% delta8) mešajte 10% ptsa in dovolj toluena, da ga raztopite, nato obdelujte

 

[kitboy]

Ko dodajam vodo, nasičeno z NAOH, da bi nevtraliziral kislino, je ne morem izločiti vse, in če dodam preveč vode, zgornja faza postane črna. Kako lahko izvedem ekstrakcijo? Kako lahko odpravim vonj po kislini? Poskušal sem ga očistiti z destilirano vodo, vendar ni pomagalo.

Potrebujem pomoč pri tem, prosim.

Kakšno PH moram pustiti THC? Ali lahko za čiščenje THC uporabim butan ali toluen?

 

[WillD]

Metode z uporabo katalitičnih količin kislin so se uveljavile bolje kot pri tej temi. S pTSA 10 % mol v DCM (delta-8) ali s HCl 0,05 % v etanolu (delta-9)

 

[Dr. MMX]

lahko uporabite drug alkohol kot etil aklohol? morda namesto tega ipa?
ali se lahko uporabi hcl?

 

[Irving Langmuir]

Mislim, da je tako, če so vaši reagenti topni. HCl se lahko uporablja kot kisli katalizator.

 

[WillD]

Sprememba topila in količina kisline močno spremenita sestavo rezultata.

 

[kitboy]

Menim, da je bolje uporabiti metanol

 

[Kvadprime]

I love vape with TGK ... I think I can do:

1. We carry out isomerization in ethanol with acetic acid for 12-24h.
2. After - we evolve all ethanol and acetic acid
3. Pour the resin with a mixture of glycerol and propylene glycol, dissolving gravs completely
4. Pour into a comfortable jar and smoke

The issue of health safety - alcohol and acetic acid should clearly not be synthetic - only food (We make THC from the CBD using trembling and sugar, aahahhaha)

Experienced isomerization specialists - what do you think? Is it worth a try?

 

[Kvadprime]

I love vape with TGK ... I think I can do:

1. Start reaction in ethanol with acetic acid for 12-24h.
2. After - we evaporate all the ethanol and acetic acid
3. Pour the resin with a mixture of glycerol and propylene glycol, dissolving gravs completely
4. Pour into a comfortable jar and smoke

The issue of health safety - alcohol and acetic acid should clearly not be synthetic - only food (We make THC from the CBD using trembling and sugar, aahahhaha)

Experienced isomerization specialists - what do you think? Is it worth a try?

 

[WillD]

You do not have to evaporate it. You can dilute with water and separate the oil if you use ethanol.

 

[Kvadprime]

Hmmm... Of course!
And question

If I use AcOH in concentration about of 70-80%, It get to start isomerisation?

Now.... I can't get or make 100% acetic acid((

 

[WillD]

Then you need 7.5 (70%) - 6.5 (80%) mL of acetic acid soln. per ~100mL of ethanol (approximately).
Excess ethanol is necessary for the reaction to go well.
The resulting solution will take 5-10 g of cbd powder, nothing more.
Heat up to 70*C and boil at least 2 hours.
Dilute with water and collect the resulting oil.
You can write us about your results after.

 

[Kvadprime]

Ok! I try to do it, thx!!

But 5g cbd in my town i cant get with good price for first try

I try with 1g cbd in 10ml ethanol with ~1ml AcOH

Thx!!!!!!!

 

[Rabidreject]

I have wanted to do this for ages but have been holding off as I don’t have p-tsa, however, if d9 is generally done with a catalytic amount of HCl, that would be MUCH easier.
Is it literally a case of chucking it all in, letting it react for ages at RT (12-24h I think I heard), quenching, extracting?

Seeing as THC is by far the drug I use the most, it would make sense for edibles or whatever. Doubt I would want to vape it though. Never was a huge fan of vaping distillate as it just screws my tolerance.

It looks pretty easy though

 

[Kvadprime]

Yes, it looks simple. That's why I want to try it!.. I'll write when I do it, there will be another report

 

[WillD]

If you use HCl for conversion, then heating is required.