Mephedrone (4-MMC) Synthesis [2B4M, Ethyl Acetate, Methylamine HCl]

[c01db100d_india_mephedron]

Vai mēs varam aizstāt

MA HCI uz
METHYLAMINE (mono) 40%
CAS.Nr.: 74-89-5

Pasūtīts

2-Bromo-4-methylpropiophenone 1451-82-7
Acetāts
NaOH
Acetons


Sakiet man, ja mums vajag vēl kaut ko?

 

[PlayTag]

Do you have any info on how it's made with methylamine aq40%

 

[handle]

Awesome, thank you for sharing this.
In step 6. Add methylamine HCL into flask Am i adding the methylamine HCl crystals? crystal / powder form?
Just thought id double check this first before i attempt.
Thanks again

 

[Dr. MMX]

Yes. You need to have flask with reaction and beaker with naoh water at room temp and methylamine hcl measured to be put in

Yes, methylamine hcl is in powder/crystals form.

 

[handle]

Thank you. sometimes reading all the posts can make things more confusing. ill try your method here first.
Try and keep it as simple as it is.

 

[Dr. MMX]

Its advized to read the whole process until every step is undersood. Its good practice - planning. If something goes wrong (if you will be confused during the process you may risk its success). If you do understand each step what to do it incrashes your chances for success

as well reading the book "lab techniques for begginers" contains priceless informations (I uploaded it into library)

 

[CARLITOBRO]

Anyway i have some questions here if you dont mind and thank you in advance

1. Used 20gr of bk4 in 100ml ethyl acetate in 500ml round bottom flask reflux attached in a water bath 40c-60c waited till all bk4 dissolved and temp reached 50c in the water bath added at once 100ml of 40%aq methylamine let it reflux for 45min and added 150ml of water and separate the organic ( by the way it was so poor yield not even 10ml yellow oil).

2.Removed while still a bit hot added 20ml ice cold acetone and begin adding 33% hcl drop by drop the solution becomes RED and quicly turned green

1.WHAT AM I DOING WRONG there is no color change after adding methyl 40%aq with stirring it just goes from opaque to yellow after 30min

2.when using ethyl acetate and methylamine aq 40% is it better to heat up with stirring OR the opposite cool it with water bath and keep to reaction cool ?

3.before acidification and ice cold acetone adding to the organic solution is it better to cool the organic phase after separating in the fridge or just added the ice cold acetone ?

 

[handle]

I read the instructions and its quite clearly states:
3. After 2b4m is dissolved, put dish with cold water, to provide cooling to flask

 

[Dr. MMX]

Hello,
1. IT seems to be a little too much of methylamine, but I dont think it could cause anything wrong at all in such scale. Your paramets seems to be ok... maybe there was too much delay between processes? it decomposes very fast.
2. it cant be hot, its advized to be cooled before
1.1 Not sure

2.1 For such scale no heating is needed, cooling as well, but i d like to strart at 40c becasue its better for reaction (for such scale)

3. yes it is, but you do that using ice bath and stirr it inside.

 

[siko]

hello
9. Sodium bicarbonate 5% H2O solution 300 ml was poured into flask with freebase then stirred for 30 mins. After that layers are
how much Sodium bicarbonate do you put in the recipe?

 

[Dr. MMX]

5% Nahco3 in h2o means 285 grams H2O and 15g of NaHCO3 (sodium bicarbonate)

 

[siko]

hello i am new are i have no experience , i hope will have it later thanks.