The class of methcathinones is the most promising direction in the modern drug market. The simplicity of synthesis opens up limitless possibilities for production in artisanal conditions, and the pharmacological activity of some variants, such as mephedrone, is simply amazing. All methcatinons are synthesized by one method. Choosing the necessary primary source - propiophenone, you can get substances of different properties.
Synthesis is easily scalable, unlike amphetamines. The availability and cheapness of the primary source makes the cost of the final product fantastically low. The average price of 4-methylpropiophenone in China is $50 per kilogram. With all the other costs for reagents, you can achieve a cost of $ 150-200 per kilogram of finished mephedrone in crystals. In the days of the legality of designer drugs, it was possible to produce a substance from the methcathinone class legal for one's country without changing the synthesis technology. Now it is possible only in Africa that loopholes in the laws remain, but in most civilized countries all metcathinons are banned.
But reagents for synthesis are legal, and even if some propiophenons are banned, you can always slightly modify the substance produced, for example: 4-MMC can be replaced with 3-MMC by replacing 4-methylpropiophenone to 3-methylpropiophenone. Or replacing 4-MMC with 4-FMC, replacing primary 4-methylpropiophenone to 4-fluoropropionphenone. In addition to changing the position of the benzene ring substituents, longer chains, such as butyrophenone or valerophenone, can be used. The latter has other properties, and is well suited for the synthesis of pyrrovalerones: a-PVP and MDPV.
If you have difficulty buying methylamine to synthesize mephedrone, then this problem can be circumvented by using legal ethylamine to produce 4-EMC, a substance with a very similar euphoric effect. In fact, from the class of methcathinones, it is possible to synthesize any substances in action, based on the availability of reagents and market needs: euphoretics and stimulants for every taste, from soft fluoromethcatinones to very hard a-PVP.
Such simplicity of synthesis and availability of reagents open up huge opportunities for capturing the market - competition with classic substances: cocaine, methamphetamine and MDMA, which are much more difficult to produce.
It is important to note one useful physical property of methcathinones - the ease of obtaining crystals. Hydrochlorides are well crystallized, as well as hydrobromides.
I have been producing various methcathinones for 15 years, many of which I have biotested personally for research purposes. If anyone has questions about synthesis, the choice of substance, the availability of reagents, then I will gladly share my experience.
Synthesis is easily scalable, unlike amphetamines. The availability and cheapness of the primary source makes the cost of the final product fantastically low. The average price of 4-methylpropiophenone in China is $50 per kilogram. With all the other costs for reagents, you can achieve a cost of $ 150-200 per kilogram of finished mephedrone in crystals. In the days of the legality of designer drugs, it was possible to produce a substance from the methcathinone class legal for one's country without changing the synthesis technology. Now it is possible only in Africa that loopholes in the laws remain, but in most civilized countries all metcathinons are banned.
But reagents for synthesis are legal, and even if some propiophenons are banned, you can always slightly modify the substance produced, for example: 4-MMC can be replaced with 3-MMC by replacing 4-methylpropiophenone to 3-methylpropiophenone. Or replacing 4-MMC with 4-FMC, replacing primary 4-methylpropiophenone to 4-fluoropropionphenone. In addition to changing the position of the benzene ring substituents, longer chains, such as butyrophenone or valerophenone, can be used. The latter has other properties, and is well suited for the synthesis of pyrrovalerones: a-PVP and MDPV.
If you have difficulty buying methylamine to synthesize mephedrone, then this problem can be circumvented by using legal ethylamine to produce 4-EMC, a substance with a very similar euphoric effect. In fact, from the class of methcathinones, it is possible to synthesize any substances in action, based on the availability of reagents and market needs: euphoretics and stimulants for every taste, from soft fluoromethcatinones to very hard a-PVP.
Such simplicity of synthesis and availability of reagents open up huge opportunities for capturing the market - competition with classic substances: cocaine, methamphetamine and MDMA, which are much more difficult to produce.
It is important to note one useful physical property of methcathinones - the ease of obtaining crystals. Hydrochlorides are well crystallized, as well as hydrobromides.
I have been producing various methcathinones for 15 years, many of which I have biotested personally for research purposes. If anyone has questions about synthesis, the choice of substance, the availability of reagents, then I will gladly share my experience.
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I have synthesized bk-MDMA following the synthesis route shared by the user @Acidosis from the precursor CAS 52190-28-0, after obtaining the HCl of bk-MDMA (a fine white powder that shines) I recrystallized said HCl of bk-MDMA with deionized water and I let it sit for several days in the open air with a transparent plastic tupperware, the problem is that I get brown or orange crystals and that means that they contain impurities, my goal is to obtain larger and purer crystals and that they are transparent (but I still don't know how).
- By plancklong
I am currently in the process of making mephedrone. I have made 4 small batches. From them all I recovered nice white or off-white product, the amounts of which lined up with the expected yields.
The problem is that none of it is active! I have snorted several 100mg lines and ingested up to a gram of each. But nothing! The precursors were sent to me; 1 kg of 2-bromo-4'-methylpropiophenone, and 2 1-liter jars of 40% methylamine in water.
Have you ever run into anything like this?
The problem is that none of it is active! I have snorted several 100mg lines and ingested up to a gram of each. But nothing! The precursors were sent to me; 1 kg of 2-bromo-4'-methylpropiophenone, and 2 1-liter jars of 40% methylamine in water.
Have you ever run into anything like this?
- By antrax
