Denne reaktion er meget god i lille skala
I en stor reaktion vil det ikke give et højt udbytte at forsøge at kontrollere eksotermen og den store mængde skum ved at hælde CuCl2-opløsningen langsomt i kolben, der vil muligvis ikke være andet end nitroalkaner, og koncentrationen af nanopartikler vil være for lille til at reducere nitro, der skal bruges den størst mulige kolbe, og hele CuCl2-opløsningen skal tilsættes på én gang.
I en stor reaktion vil det ikke give et højt udbytte at forsøge at kontrollere eksotermen og den store mængde skum ved at hælde CuCl2-opløsningen langsomt i kolben, der vil muligvis ikke være andet end nitroalkaner, og koncentrationen af nanopartikler vil være for lille til at reducere nitro, der skal bruges den størst mulige kolbe, og hele CuCl2-opløsningen skal tilsættes på én gang.
- By waltjr5858
But when you add all of the cucl2 at once the whole mixture turns black and then within minutes the catalyst falls out of the alcohol and doesn't do much down low... adding drop wise allows a continuous supply of copper to stay in the upper layer acting as a catalyst. So far I have found if you have too much nabh4 left at the time of adding the copper the copper gets reduced wayyy to fast and losses its catalyst activity instead of almost starting as a yellow or brown mixture and slowly turning black before finally falling to the bottom. Thise are the reactions that really work for me when the borohydride amount is low enough to not instantly reduce the copper to black and need the temperature increase to finally cause it to be fully reduced and settle in the bottom slowly over time.... but trying to get the perfect amount of nabh4 at that moment is let's say.... very difficult. Surprisingly the nitro doesn't need much nabh4 in the end to reduce.
