Methylaminhydrochlorid-syntese. I stor skala.

[handle]

En noget enklere mulighed for at producere methylamin ville være at reducere nitromethan CH3NO2 til methylamin CH3NH2 via Al/Hg-amalgam.

CH3NO2 + H2 ---> CH3NH2+ H2O

 

[Osmosis Vanderwaal]

Jeg føler, at der er en grund til det, for det er almindeligt at bruge modelflybrændstof til at lave methylamin in vitro... enten nedbrydes det hurtigt, eller... det lyder som en energisk reaktion.

 

[handle]

Varmt, tungt og hårdt! Min hjerne gør ondt nu. Jeg havde tænkt mig bare at opsamle al den gas, der slipper ud af rxn, i noget HCl og dumpe resten. Eller bruge insitu uden forsinkelse.

 

[Osmosis Vanderwaal]

Her er grunden til, at det reducerer det til alkohol (overreducerer det, det er det, Rhodium siger med "den fremherskende reaktion....." https://chemistry.mdma.ch/hiveboard/chemistrydiscourse/000460257.html

 

[Kylemalone1297]

Can u wash the methylamine with ethanol instead of chloroform? I have so many chemicals this is getting to be a small chem store.

 

[NovicechemistEU]

Tomorrow I will do an experiment.
9.34 mol **500 grams of ammonium chloride (NH₄Cl)
formaldehyde 37% (CH₂O) 12.7 mol approx. 1030 grams
Dcm and methanol

 

[NovicechemistEU]

I made the synthesis with a last minute decision in 3 lt capacity. The yield was good, I got 270 grams.
Ammonium chloride (NH₄Cl) 749 Gr
formaldehit %37 (CH₂O) 1546 Gr

 

[NovicechemistEU]

The product of tonight's synthesis is methylamine HCl.
Tomorrow I'll make a different synthesis, 750 +1500 gr
.

 

[NovicechemistEU]

My latest synthesis is methylamine HCl. It looks better this time, the next one will look better
I can't thank the forum enough.
The next synthesis is coming soon
1000+2000 Gr

 

[NovicechemistEU]

Hi Bb team, I'm going to synthesize methylamine this weekend I'll make a slightly bigger batch. Ammonium chloride (NH₄Cl) 1250 g
formaldehyde 37% (CH₂O) 2500 g (with 15% methanol)
I'll write the results

 

[Osmosis Vanderwaal]

Have you done a confirmatory test that its in fact methylammonium chloride and not ammonium chloride?