Extrakce psilocybinu a psilocinu z hub

[G.Patton]

~20-30%

 

[Neo156773]

Do you know if 4-aco-dmt freebase is soluble in ethyl acetate and if yes how many mg/ml ?

and is ethyl acetate a nice solvent to dissolve a mix of psilocin freebase & acetic anhydride (1,1mol e.q) & sodium acetate (0,1 mol e.q) ( acetylation process of psilocin —> 4-aco-dmt)

maybe for better yield performing acetylation process under influence of nitrogen ballon to reduce oxidation and humidity ) -> then after acetylation neutralize tensing acetic anhydride with water to the ethyl acetate (which contains acetic anhydride & Psilocin freebase & sodium acetate Then adding a bit sodium hydroxide to pH 10 and then extracting 4aco dmt freebase again (should hopefully end in ethyl acetate layer/phase). Then drying ethyl acetate with sodium sulfate and then rotary evoporation to obtain 4aco dmt freebase.
Then dissolving in hot acetone (jar 1) und also dissolve the right amount of fumaric acid in acetone (jar 2). Then mixing (jar 1 and 2) and stirr for a few mins on a magnetic stirrer and then rotary evaporation to obtain 4-aco-dmt fumarate ( for long term storage free from humidity/light/oxygen & maybe in the refrigerator ) what do you think ?

 

[G.Patton]

Hello, I don't know for sure about solubility. I assume yes.

 

[G.Patton]

Dobrý den, omlouvám se za dlouhou odpověď. Ano, můžete. Postup je stejný.

 

[Neo156773]

It does not work for amanita
A/B-tek does not work because Muscimol freebase is still not soluble in organic solvents like ethyl acetate.
I tried it.
You can try to extract with 10% acetic acid and then defat with xylene/ethyl acetate.
But basing with ammonia (pH 8-10) and then extracting with organic solvent won’t work

 

[Neo156773]

Nobody said that amanitas contain psilocybin?
he/she asked if it’s possible to do an a/b tek for amanitas ( for Muscimole hydrochloride I guess) and the answer is no

 

[Neo156773]

Muscimole is very polar even as freebase. It will prefer the aqueous layer and not the organic layer (toluene/naphta/xylene/dcm/ethyl acetate).
That’s the problem.
I tried it with xylene and yield was very bad

 

[Osmosis Vanderwaal]

well it was posted in a thread on psilocin/psilocybin extraction . and not everyone is aware of soma and english is his secnd language, so it's likely he didn't realize you were talking about not psilocybiasn mushrooms because that is off-topic in this thread.