Synthesis of JWH-167 with peperine

[chemistrydude]

Peperine structure scheme

Wanted product structure scheme​

Reagents: C17H19NO3, CH2Cl2, NaOH, C5H11Br, C3H6O, H2O, C3H8O

Okay let's start synthesis,first of all put NaOH into flask like 40 grams, if you need 8 gram of product, and adding 215ml of cold water mix it, it will be needed later. And now let's extract peperine, adding 110 gram of black crushed peppers into other flask and add 220ml of CH2Cl2, now let's put us flask with black peppers and CH2Cl2 on plate the temperature 145 °C and add teflon magnet, and wait for crystals(the color is yellow), and now we need to filtrate, and we have peperine 97.7% pure peperine(in grams is 25).
Now put in other flask 25 grams of peperine and add 58ml of amyl bromide, mix it together with 12ml of acetone, now we should to wait when our mixture was crystalizated like 7 hours, and now is completely crystalizated, and that's why i said you need NaOH let's add 215ml of NaOH, and it's time for filtrate, wash crystals with isopropyl alchogol and put in bowl us maded product, wait for dry.
Congrats now you have 8 grams of JWH-167

 

[G.Patton]

Please, give IUPAC name of substances.

 

[chemistrydude]

Well you right

 

[chemistrydude]

C17H19NO3 is peperine, CH2CI2 is dichloromethane, NaOH is sodium hydroxide, C5H11Br is amyl bromide, C3H6O is acetone, H2O is water, C3H8O is isopropyl alchogol

 

[XenocodeRCE]

so a few words

piperine needs to be pure, pepper contains other chems you need to remove or simply buy pepper extract powder as cheap as € 14,44 / 50g on aliexpress

DCM is carcinogenic, better to replace with ethyl acetate, can be found legally on cosmetic store, pure as cheap as € 29 / 5L

what sodium hydroxide you used ? mol/L ?

n-Amyl bromide not allowed for domestic buy so good luck



this kind of recipe can be dangerous, its not precise at all

 

[chemistrydude]

I know, i recommend go outside with chemical protection

 

[Khaled]

Hello, how are you? This method has already been tested. Is the output strong?

 

[woohoo]

How its possible? Draw formula please.
Looks fake.