Question Purifying Amphetamine Base

[Mohammed_Lee]

Hi there,

is there a way to distill solvents of Amphetamine Base without a rotavap?

All the best,

Lee

 

[CaptainSandoz]

Depending of the quantity and nature of solvent, if in lower amount than the base and if your solvent have a low boiling point or if it is - under 90°C and non polar - you can just strip it under your hardest vacuum keeping your flask in gentle water bath. 30-40°C. Better to use a water pump for that or have a washing flask to keep your pump free of solvent. I bet you are talking about IPA, if it is you can simply dry it and acidify to get the salt and perform a recryst, if you really want If as oil you can simply do a vacuum distillation of the two products with eventually a short Vigreux.

Best Regards,

Captain Sandoz

 

[Mohammed_Lee]

Thank you for the long answer!