ICE-Making Meth the Right Way D-Methamphetamine hydrochloride

[Grubby]

You don’t want to be fooled by videos on the forum again, do you? I spent more than a year to successfully make the real process D-methamphetamine hydrochloride
No remarks are uniform at room temperature and pressure
Written by myself
1. Prepare raw materials
20ml P2P
100ml 20% methylamine methanol solution
4g NabH4
1/3 RM 3A molecular sieve (silicon dioxide)
Glacial acetic acid
HCI (concentrated hydrochloric acid)
Sodium hydroxide
Dichloromethane
D-tartaric acid
Anhydrous magnesium sulfate (anhydrous sodium sulfate)
Ether
Ethanol (isopropanol)
2. Generate imine
Add the methylamine methanol solution and P2P to the flask containing molecular sieves, shake evenly, seal and let stand for 6 hours to generate the imine intermediate.


3. Amination reduction
Prepare a container and pour NaBh4 into it. Dissolve it completely in methanol and then pour in the molecular sieve. Add 1 drop of NaBh4 methanol solution per second to the imine intermediate in an ice bath below 10 degrees and add a trace amount of glacial acetic acid. After all the NaBh4 has been added, remove the RM from the ice bath for reductive amination. Do not cover the bottle too tightly and stir for 2 hours to generate methamphetamine.


4. Acidification and evaporation
After removing the molecular sieve, add hydrochloric acid until the pH value of RM is 3, heat and evaporate until the boiling point is close to 100, then add appropriate amount of water and evaporate to the boiling point of 100 to ensure that the methanol is completely removed.


5. Acid-base extraction
RM was poured into a separatory funnel, dichloromethane was added, shaken, and the organic layer was discarded. The aqueous phase was retained, sodium hydroxide was added to a pH value of 12, and then poured into a separatory funnel. New dichloromethane was added to remove the aqueous phase, and the dichloromethane was concentrated and washed with water (twice). After drying with anhydrous magnesium sulfate, a pure free methamphetamine dichloromethane solution was obtained.


6. Steam distillation
After evaporating dichloromethane, use steam to distill out all the free methamphetamine, pour all the liquid in the receiving bottle into the separatory funnel, let it stand and separate the layers, discard the water phase, and obtain pure free methamphetamine

7. Right-handed splitting
Dissolve 6g of D-tartaric acid in the minimum amount of ethanol, heat to boiling, pour into a beaker containing 20g of free methamphetamine, stir evenly while hot, let it stand and crystallize at the bottom, and extract the free D-methamphetamine on the upper layer with ether

8. Acidification crystallization
Add anhydrous magnesium sulfate to dry the free D-methamphetamine extracted with ether, filter out the desiccant, and then introduce hydrogen chloride gas to a pH of 6. Heat and evaporate until it is nearly dry and let it stand and crystallize, which is D-methamphetamine hydrochloride.

 

[rampage]

hey bro thanks for your effort and good write up

 

[GhostChemist]

You can make your own video on this topic
Why not?

 

[GhostChemist]

Why are the yields (in stages 6 and 8) of reaction products not shown?

 

[Grubby]

I think it's a translation issue... I'll reply to this post to add the details. The second stage: methylamine methanol solution + P2P + 0.2ml acetic acid, acid as catalyst (not suitable for NaBH4) stirred for 6 hours to generate imine. The third stage: stir the NaBH4 methanol evenly and dry it. It took more than 2 hours for RM to quantitatively titrate NaBH4 under ice bath, and stirring was continued for 2 hours (amination reduction required more than 4 hours in total). Period 6: Drying Solvent Evaporation Collect 18 mL (16 g) of pure free base in a measuring cup. Stage 7: Confirm that the Cas number of D-tartaric acid (147-71-7) is more accurate and reliable than its name. 13 g of D-tartaric acid was dissolved in 52 ml of methanol and poured into RM (D-base-L-base) to generate diastereomers (D acid-D-base salt) and (D acid-L-base salt). Stir overnight. The isomer (D acid-L base salt) has a higher solubility and remains in the liquid, while the (D acid-D base salt) has a lower solubility and precipitates as crystals. The crystals were filtered and dissolved in an alkaline solution to pH 12 to separate free D-methamphetamine oil and D-tartaric acid water. Free D-methamphetamine was extracted with ether and saturated aqueous sodium chloride solution using a separatory funnel and collected in a beaker. Stage 8: The RM obtained in the previous step with HCl gas has a pH of 6 and is in a dry state. It is heated and evaporated to near dryness, isopropanol is added to dissolve, and then heated and evaporated to near dryness. It is cooled and allowed to stand for crystallization: weigh and deduct the weight of the beaker to obtain: 6g D-ICE dextrorotatory methamphetamine hydrochloride Cas (51-57-0). 185.68÷134.18 = 1.383×20 = 27.676÷2 = 13.383.6÷13.383 = 0.448×100% = Rate of return 44.8%. Although not high, it is still a more realistic rate of return than the fake 90% (maybe 0-9%) rate of return in plagiarized papers.

 

[GhostChemist]

What do you mean about fake and plagiarized papers? I would read them with interest
I don`t understand this calculations "185.68÷134.18 = 1.383×20 = 27.676÷2 = 13.383.6÷13.383 = 0.448×100% = Rate of return 44.8%"
And more very interesting weight of crystals that were filtered before dissolved in an alkaline solution to pH 12

 

[Grubby]

I think it depends on how you understand it. If you say it's all true, that's fine. It's just that didn't mention too many important factors and details and took it for granted that it's common sense for ordinary people or said it's free and you have no opinions, etc., without forcing others or deceiving others, so strictly speaking, there is no problem
Just like I didn't name any article or forum as a scam. Strictly speaking, I haven't criticized anyone.

The mass of the target product dextrorotatory methamphetamine hydrochloride is 185.86 The mass of the raw material P2P is 134.18 The dosage is 20 = theoretical yield (d/l) Meth 27.676g, the target product (D-Meth accounts for half) so 2 is the target theoretical yield 13.383 The target actual yield is equal to the yield 0.448=44.8% which means that if the yield is 100%, the yield is 13.383g. My yield is 6g, and D-Meth only accounts for 44.8%, so the yield is 44.8%. Here is the calculation process: 185.86134.18=1.38320=27.6762=13.3836=0.448=44.8%
can tell at a glance that I am not a professional. It is normal for my algorithm to have problems with expression or logic. You can use professional methods to calculate my yield.

 

[Vyjebanec1]

Amazing manual how to explode Like a Czech guy I really can't believe, how difficult ways you are using to make piko

 

[rampage]

if you have an easier method please provide details?

 

[Grubby]

If you know of a better way to make it, please feel free to share it. Even if you post the link to the paper, it may help everyone. I also want to learn a more optimized process.

 

[G.Patton]

Dear @Grubby, BB Forum is made not to "fool" anyone. We make videos, post it for free and support by other related information in order to give people chance to do it by your own. There are some people like you wanna hate this and badmouthing us because they have own self - serving motivations. Want to mislead people or gain some reputation by this. To be honest, I don't know what is your motivation, but we'll look after you more carefully.

 

[Grubby]

Dear idol, I'm sorry for my behavior. My motives may have been meaningless. I can't think of it, but I remember posting a post criticizing the forum. So, I'm sorry. I must have had the side effects of taking drugs at the time (this is not an excuse). Sorry

 

[handle]

(I can't think of it, but I remember posting a post criticizing the forum.)
Bro! its in this post!
first line> You don’t want to be fooled by videos on the forum again, do you? I spent more than a year to successfully make the real process D-methamphetamine hydrochloride.

 

[rampage]

I'm about on par with that! roughly 16k so far lol, thats not taking into account how much been spent on getting high roughly 200-300k over 30yrs, but thats okay because what really matters is the now, im free!

 

[Grubby]

I think I just used radical words at the beginning just to deepen my own psychological feelings when I was constantly failing so that I could resonate with everyone and attract more attention so that more people can learn my own methods.

 

[G.Patton]

It's not our fault that you can't reach success in syntheses, which have repeated by others many times with proves.

 

[rampage]

if one was to use L-tartaric acid in step 7, would the process be the same? so the d-meth would crystalize out and the l-meth stay in solution?

 

[Grubby]

 

[Grubby]

If there is no crystallization after the tartaric acid of (-)-tartaric acid CAS (147:71:7) is added and dissolved, it can be evaporated to crystallization or more tartaric acid can be added to crystallize. The crystals contain dextrorotatory amine. Add alkali solution to separate oil = dextrorotatory amine, water = tartrate. If yours is dextrorotatory tartaric acid, L-tartaric acid, d-tartaric acid, (+)-tartaric acid CAS (87-69-4), then the crystallization part is the opposite. You just need to remember to check the CAS number for accuracy. The name part will be painful for novices to understand and it is not very meaningful. As for the pH value, it is acidic according to my ratio and there is no need to deliberately adjust the pH value of the two isomers in RM. The order of crystallization is the same. This is the actual operation.

 

[hirozaru]

This indeed looks awesome ... I did not carefully look at every step, only the end is useful to me.
Because I do not have access to the same starting material. I go have Glacial Acidic acid though.

Hard to say if I am lucky or not, but I got access to PSE, No Phosforus, or Iodine.
But I have NH4NO3, NaOH, KOH, Methanol, Isopropyl.

Can you help with improving my one-pot reaction ? scaling it to do 10g the time...

I am strongly considering the purchase of a freezer that goes down to -60C.
My plan with it, is to mix NaOH with NH4NO3 in a bucket, have the NH3 has escape through a tube/hose going from the ambient room temperature to a bucket in a freezer, it should go liquid. I will have pure liquid NH3, in which I can easily dissolve Lithium.
When Lithium is dissolving, some Hydrogen gas, or maybe Hydrogen Chlorine gas is being released as a by product. I thought of collecting it into a plastic back for salting later.

Otherwise, for the one-pot reaction, I prefer to salt by pouring HCl acid, instead.

now the bit that's unknown... is can I just pour my extracted PSE, or my grinded pill content in there?

How will it react ? How long ? How do I know the reaction is complete?
How do I separate thing back? filter inside the freezer? Can I reuse the liquid ammonia multiple times?

I would love to have your help, or anyone's help on this.


cc: @insp @spider

 

[Grubby]

Please keep this amount for purchasing equipment or reagents needed in the production process of this article. You mentioned that the reagents you currently have are all useful, but none of the reagents mentioned in the article can be missing unless you have an {absolutely suitable} alternative reagent~
I’ve never made the one pot method so I can’t teach you. But I know that the one-pot method usually requires high temperature, is difficult, dangerous, and has low yields, so I recommend not using the one-pot method. Reducing P2P with NaBH4 is more advantageous in every aspect

 

[rampage]

whats your method for making 20% methylamine methanol solution?

 

[Grubby]

30%MMA/MeOH I think our way comes from here

20%MMA/MeOH/315ml&15%MMA/MeOH/470ml
100g Methylamine hydrochloride (593-61-1)
250g methanol (315ml)
60g sodium hydroxide
Anhydrous sodium sulfate, 3A molecular sieve (appropriate amount)

Standard concentration version concentration> 20%
Add magnetron, methylamine hydrochloride and methanol to the reaction flask, soak the flask in an ice-salt bath with stirring, slowly add sodium hydroxide to keep the temperature low, seal after all the additions are made, release the pressure occasionally, stir evenly for 30 minutes, filter out the liquid, add anhydrous sodium sulfate, dry, and filter out to obtain a 20% methylamine methanol solution, add 3A molecular sieves, seal and store.

Optimized simplified version concentration>15%
Soak the flask in an ice bath and add a magnet, methylamine hydrochloride and sodium hydroxide in order. Turn on the magnetic stirring and add 375 g of methanol and seal the flask (release the pressure appropriately). Stir evenly for 5 minutes, cool and filter out the liquid. Add anhydrous magnesium sulfate, dry and filter out to obtain a 15% methylamine methanol solution. Add 3A molecular sieves and seal the flask for storage.

 

[Grubby]

In fact, the theoretical yield is 25% concentration without any methylamine or methanol evaporation. The concentration of 30% means that it can only be produced when more than 200g of methanol evaporates and 0g of methylamine evaporates. Therefore, it is actually impossible to exceed 25%, because there must be more methylamine than methanol, and the actual concentration will only be lower than 25%. This is why my yield is low, but the data must be true.