Hey i was just looking around the threads and want to share my experience with this synthesis ( as i didn't find any report for this in moderate scale )
I HAVE DONE THIS PROCEDURE ABOUT 4 TIMES BY NOW AND WOULD LIKE TO SHARE SOME OF IT.
EQUIPMENT USED
500ML FLAT BOTTOM FLASK
500mm ALLIHN...
Stage 1. Synthesis of Piperonal.
Extraction of piperine from black pepper has been demonstrated previously.
Starting reagents and materials
5 g recrystallized piperine
100 + 50 ml THF
10 g Potassium permanganate + 200-300 ml water
800-1000 ml DCM
50-100 g anhydrous sodium sulfate
25 ml EtOH...