ephedrine from propiophenone

Starting Reagents and Materials 6 g Synthetic ephedrine hydrochloride racemic 12 g I2 10.8 ml H3PO2 (50%) 20 ml H2O 50 ml 25% NaOH (15-20 г NaOH) 3 g sodium thiosulfate 250-300 ml DCM 30-50 g Na2SO4 100 ml Petroleum ether HCl gas 100 g NH4Cl 25 ml H2SO4 83% Flasks 250 and 500 ml Glasses Funnels...

THEORY OF SYNTHESIS OF EPHEDRINE. The mechanism of these reactions is well known: - at the first stage, bromine is attached to propiophenone in benzene, alpha-bromine-propiophenone is obtained; - at the second stage, bromine is replaced by an amino group, cathinone is obtained (if ammonia is...