Question I need help, who knows N-BOC NORKETAMINE, your help will not be free
- Thread starter hider8028
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hey i just looked it up and a site said
"Norketamine (5) is a major metabolite of ketamine (4) that is produced by cytochrome P450 enzymes in the liver. It goes on to be hydroxylated to form (2R,6R)-hydroxynorketamine. The latter compound also has a promising antidepressant activity but differs from the aforementioned derivatives in the sense that it is inactive both as an anesthetic and a psychostimulant."
im pretty sure n-boc norketamine is a derivative of norketamine with a protective ring. idk if that has any effects on functionality though. is this what u were looking for or do u need something else? feel free to pm me
"Norketamine (5) is a major metabolite of ketamine (4) that is produced by cytochrome P450 enzymes in the liver. It goes on to be hydroxylated to form (2R,6R)-hydroxynorketamine. The latter compound also has a promising antidepressant activity but differs from the aforementioned derivatives in the sense that it is inactive both as an anesthetic and a psychostimulant."
im pretty sure n-boc norketamine is a derivative of norketamine with a protective ring. idk if that has any effects on functionality though. is this what u were looking for or do u need something else? feel free to pm me
N-BOC stands for N-benzyloxycabonyl which is indeed a protecting group due to its ease of removal and it may help either with the monoalkylation of the substrate or it needs to be removed prior to the alkylation. N-BOC derivative may be not considered neither a drug nor a precursor in some places where the law is such.