Question about some synthesis

[chemicals]

I am interested which one of the following stuff is the easiest and cheapest to sythetize: a-pvp/a-php/a-pihp, mdpihp/mdphp, nep

 

[HIGGS BOSSON]

The cheapest will be a-PVP, because the synthesis is easy with good yields, and alpha-bromo-valerophenone is produced in large quantities in China, the reagent is legal and available at good prices. In addition, a-PVP has the best effect among its analogues