Question MDP2P FROM PIPERONAL

twok

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in the synthesis of piperonal and nitroethane, Could I replace it with nitromethane?
 

Grandthumb123

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The synthesis of piperonal and nitroethane both involve the use of nitroethane as a reagent, and it is not recommended to replace it with nitromethane without careful consideration of the reaction mechanism and the specific conditions of the reaction.

In the synthesis of piperonal, nitroethane is used as a reactant in a nitroaldol reaction with aromatic aldehyde, followed by a cyclization reaction to form piperonal. Nitromethane may have different reactivity and selectivity compared to nitroethane, which may lead to different reaction products or side reactions. Additionally, the reaction conditions such as temperature, pH, and solvent may need to be adjusted if nitromethane is used instead of nitroethane.

Similarly, in the synthesis of nitroethane, nitroethane is used as a reactant in a nitroalkane synthesis reaction with an alkyl halide. Again, nitromethane may have different reactivity or selectivity compared to nitroethane, and the reaction conditions may need to be adjusted accordingly.

Therefore, while it is theoretically possible to replace nitroethane with nitromethane in these reactions, it is not recommended without careful consideration and experimentation to determine the suitability of the substitution.
 

auc

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Is there any other way to replace the nitroethane with another method?

This product is practically not available
 

HIGGS BOSSON

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Formulate your question more clearly.
What do you want to get as a result of synthesis?
If your goal is methylenedioxyphenylnitropropene, which is obtained from nitroethane and piperonal, then it is impossible to replace nitroethane in this case.

Nitroethane can be bought, there are many suppliers working for the gray market in our listing.
 

Brumer.com

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we offer quality nitroethane. $200 per kilo, If you buy more, you get a lower price. When buying 100kg, a kilo will cost $150. We have a flexible payment system, safe delivery. We give discounts to customers. Write to us
 
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