Question MDP-2-P —> MDMA best way

jzsmluka

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As far as I know there are 2 decent ways of doing this. One consists of going with the NaBH4 reductive amination and the other one uses Al/Hg. Which one would be better for a first timer? My top priority is getting high yields and purity. I’m a good chemist so complexity of the procedures shouldn’t be an issue.
I just want to know which one would be more suitable for high purity and yield MDMA.

Thanks!!
 

Katty Korner

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Seems using sodium triacetoxyborohydride produces really good yields, probably very clean too, assuming good reagents, solvents, etc
 
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