BMK Glycidate: Comprehensive Guide to Methyl, Ethyl, and Powder Forms

Understanding the Chemistry

Understanding the chemistry behind the conversion of BMK Glycidate to Phenylacetone (P2P) requires delving into its precursors like BMK Methyl Glycidate and BMK Ethyl Glycidate. In this article, we break down the process for you.

Phenylacetone (P2P)

Advantages of This Synthesis:

  • Insensitivity to water, unlike BMK methyl glycidate synthesis.
  • High yield conversion: Remarkably, an 82% transition from benzaldehyde to P2P is achieved.
  • Simple equipment requirements, making it scalable for various laboratory sizes.

Did You Know? This process isn't just about creating P2P. It’s also about how to synthesize BMK Ethyl Glycidate from benzaldehyde.

Required Equipment and Glassware:

Equipment/Glassware Quantity
Four-necked round bottom reaction flask (3 L) with reflux condenser, top stirrer, and pressure-equalized drip funnel (250 mL) 1

Essential Reagents:

Reagents Quantity
Dimethylformamide 900 ml


Steps for Synthesis:

  1. BMK Ethyl Glycidate from Benzaldehyde:

    BMK Ethyl Glycidate from Benzaldehyde

    The process starts by converting benzaldehyde into BMK ethyl glycidate. Here's how:

    • Begin by pouring 900 ml of Dimethylformamide into the 3 L four-necked flask.
  2. BMK Glycidic Acid (Sodium Salt) from BMK Ethyl Glycidate:BMK Glycidic Acid (Sodium Salt) from BMK Ethyl Glycidate

    Once you have the BMK ethyl glycidate, the synthesis of BMK glycidic acid (sodium salt) becomes the next milestone.

    • Return the glycidate ester to a clean flask.
  3. Phenylacetone (P2P) from BMK Glycidic Acid (Sodium Salt):Phenylacetone (P2P) from BMK Glycidic Acid (Sodium Salt)

    The final step is converting the BMK glycidic acid (sodium salt) into Phenylacetone (P2P).

    • Carefully introduce concentrated (37%) aqueous hydrochloric acid (HCl) into the flask, aiming to reach a pH level of 1.


Additional Insights on BMK Ethyl Glycidate to P2P Synthesis:

BMK Ethyl Glycidate synthesis and the subsequent conversion to P2P represents a cornerstone in organic chemistry, often serving as an intermediate step in the synthesis of various organic compounds.

Safety Protocols:

Always ensure a well-ventilated laboratory space when performing the synthesis. Wear appropriate personal protective equipment, including gloves, lab coat, and safety goggles. P2P and its derivatives have been noted for their flammability, hence avoiding open flames or any ignition sources is crucial.

Purity Concerns:

The purity of the starting materials, especially BMK Ethyl Glycidate, can have a significant impact on the end product's yield and quality. It's recommended to source high-quality reagents and ensure their proper storage to avoid degradation.

Scale-up Considerations:

When scaling up the synthesis for industrial or large batch production, it's essential to monitor the reaction temperature closely. Larger volumes can lead to varying heat distributions, affecting the reaction's efficiency and yield.

Environmental Impact:

It's important to consider the environmental implications of the synthesis. Dispose of waste products in accordance with local regulations. Ideally, aim to develop sustainable methods that minimize waste generation.

Alternative Methods:

While the presented synthesis method offers good yields and is relatively straightforward, there are other pathways to produce P2P. Research continues to find more efficient, less hazardous, and more environmentally friendly methods.

By considering these factors and continuing research in the field, chemists can ensure efficient, safe, and sustainable production of P2P and its related compounds. Always stay updated with the latest literature and guidelines to optimize and improve synthesis procedures.

  1. Precursor-supplier

    Looking for strong and reputable wholesalers in Europe,

    Looking for strong and reputable wholesalers in Europe, Cash on delivery, if the goods are lost or detained by customs, I will resend the goods without any risk. Delivery to German warehouse, need to pick up. WA Business/Telegram:+86 19965197035 Telegram/Signal:+852 90624891...
  2. W

    BMK Glycidic Acid (sodium salt) CAS 5449-12-7

    Payment Terms: TT, Bitcoin, USDT, XMR, Western Union, MoneyGram, Escrow Delivery: 100% safe, fast, secure, and discreet with undetectable packaging and delivery worldwide Germany Netherlands UK Poland Warehouse Spot Stock (Poland spot stock: 900Kg; Germany spot stock: 300Kg) Price: 1Kg USD130...
  3. Ada.

    CAS 25547-51-7 BMK glycidic acid

    CAS 25547-51-7 BMK glycidic acid Product Name: BMK Glycidic Acid Synonyms: BMK Glycidic Acid;trans-α,β-epoxy-α-methylcinnamic acid;2-Oxiranecarboxylic acid, 2-methyl-3-phenyl-;trans-α,β-epoxy-β-methylcinnamic acid;BMK Glycidic Acid Basic information;trans-α,β-epoxy-α-methylcinnamic acid...
  4. Precursor-supplier

    BMK Glycidic Acid (sodium salt) CAS:5449-12-7

    Chemical Name: BMK Glycidic Acid (sodium salt) CAS : 5449-12-7 Origin in China Price: $70 / kg Molecular formula: C10H11NaO3 Molecular weight: 202.18 Synonyms:BMK Glycidic Acid (sodium salt); sodium,2-methyl-3-phenyloxirane-2-carboxylic acid; 2-methyl-3-phenyloxirane-2-carboxylic acid; sodium...
  5. G.Patton

    Phenylacetone (P2P) synthesis via BMK ethyl glycidate

    This phenylacetone (P2P) synthesis approach is a simple way how to get phenylacetone from BMK ethyl glycidate and its synthesis from benzaldehyde. PMK ethyl glycidate can be hydrolyzed into P2P. This reaction isn't sensitive to water like BMK methyl glycidate synthesis. There is such advantage...
  6. S

    BMK ethyl glycidate CAS 41232-97-7

    Product Name: BMK ethyl glycidate CAS NO: 41232-97-7 EINECS: N/A Molecular Formula: C12H14O3 Molecular Weight: 206.24 Formulation: DMF: 20 mg/ml; DMSO: 25 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 1 mg/ml Density: 1.3±0.1 g/cm3 Appearance: white solid
  7. H

    P2P synthesis from BMK Glycidic Acid (sodium salt) - modified version

    Introduction This is the modified preparation of P2P CAS 103-79-7 made using BMK Glycidic Acid ( sodium salt ) CAS 5449-12-7 with Phosphoric Acid 85% CAS 7664-38-2 Equipment and glassware: 1000 ml 3-neck Round bottom flask Distillation adapter Condenser with a receiving flask Dropping funnel...
  8. G.Patton

    BMK glycidate (sodium salt) synthesis from benzaldehyde

    Introduction This synthesis is a good option in case you have unavailable phenylacetone for further amphetamine or methamphetamine synthesis. BMK glycidate can be easily turn into P2P by hydrolysis. This reaction have some pros and cons. The main disadvantage that reaction is very sensitive to...
  9. Daisy

    Top Fine Chemicals Supplier-Wuhan Wingroup(WGP)

    We'd like to be your trusted partner with our high-quality materials, affordable price and responsible customer service.
  10. G.Patton

    P2P synthesis from BMK glycidate ethers

    Introduction Hydrolysis of BMK glycidate ethers is represented in this topic. The procedure is the same for ethyl (Et) [cas 41232-97-7] and methyl (Me) [cas 80532-66-7] esters of glycidic acid. In case of sodium (Na) salt of this acid [cas 5449-12-7], you can skip first stage of NaOH addition...
  • Free product samples

    Testing products from new vendors and manufacturers.

    Get free samples for testing now!

  • The BB Forum team is looking for cooperation:

    • Traffic arbitrage specialists
    • Spammers
    • Advertising agencies
    • Bloggers/Vloggers
    • TOR sites directories
    • Creative people who can create viral content
    • Administrators of Telegram Channels and Groups

      We will pay more for your traffic than our competitors! $0.1 per visitor!!!If you are interested in, write to the administrator.